There is little evidence based information on potential drug to drug interaction. Because marijuana tends to have a sedative effect in most cases, it should be used with extreme caution in combination with any drug or supplement that also has the potential to cause a sedative effect. These drugs classes include but are not limited to: Opiates, benzodiazepines, barbiturates, SRI’s, over the counter sleep aides, over the counter allergy medications (especially those containing histamines), supplements that intended to create a sedative effect or sleep.
OTC MEDICATIONS NOT TO BE TAKEN WHILE USING CANNABIS:
∙ NSAID’S for pain such as ibuprofen, Aleve, etc.
∙ Antihistamines such as Benadryl, Claritin, Allegra, etc.
∙ Caffeine containing medicine such as the many products for pain, headache, etc.
∙ Stomach acid inhibitors such as Zantac, Prilosec, etc.
∙ Saint John’s Wort
∙ Ginkgo biloba
In taking any medicine with cannabis, prescription or otherwise, patient should discuss the matter with their medical provider.
Cannabis alone has never caused death, but combining drugs, prescription or over the counter, can have unforeseen results.
For specific drug interactions, go to: www.drugs.com/drug-interactions/cannabis